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Hidden Markov Models for Molecular Motors

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important script information
company name:
Fred Sigworth
license: Free
minimum requirements: MATLAB 7.8 (R2009a)
functional limitations:
Hidden Markov Models for Molecular Motors description
Hidden Markov models are used to describe the "stepping" behavior of molecular motors, as measured by single-molecule fluorescence techniques. Our HMM implementation is more versatile than the one described by Milescu, et al. Biophys. J. 91:3135-3150 and can be used as a "blind" step detector or to find rate constants and step sizes directly from a measured time course of positions. A manuscript is in preparation (write to me for a copy at fred.sigworth@yale.edu). Meanwhile a readme file and example script demonstrate the use of the functions.
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